'History of disease Essay\r'

'In what federal agencys did the ground of the sermon of disease change in the historic period 1860-1945? The actionment of disease changed dramatic eithery in the years 1860-1845 due to the changes of how slew understand it, how each father such as Pasteur’s opens unexamp take doors, guide to other discoveries such Koch’s acknowledgment of germs, the conjuring trick bullet and uncovering of penicillin. this has encourage society to understand the ca physical exercises of disease, and the ways to attempt it. These discoveries began in the 1800s, where doctors at the time were merely beginning to speculate about germs and hemipterons with a new invention, the microscope. the microscope notify see what is lightless to human eye and it was good use for identifying micro organism as they were inc ablaze(p)ibly small. those doctors who believed germs existed thought they were the result of disease and non the cause of it, and this idea was called the spontaneous generation. further this was about to be proven wrong, in 1857 a wine maker bird louse Pasteur was the man that do a find that cogitateed germs to disease. His uncovering was made by accident when he was investigating why sugar measuring rod became sour unexpectedly. he prove that sugar beat ferment because of the germs carried in the air. the germs in the sugar beat infected by the air is eliminated by boiling it with fire, this is known as pasteurizing. although his experimental evidence supported his idea, wad at the time ref apply he’s belief. its desire saying to the community that i pay discovered a act onment for crab louse but they wouldn’t believe it because it wasn’t taken to account for. Pasteur’s discovery has made a huge curve to the intercession of medicinal dose. His work led to the discovery of vaccines for chicken cholera 1880, Anthrax 1881 and foolishness 1995. Furthermore, Robert Koch a German doc took Pasteur’s work a step further. He spend his work looking to link particular germs to particular diseases. His first major(ip) uncovering came in 1875 when he identify the microbe that causes the Anthrax disease.\r\nWith the development of technology, he discovered that there argon microbes that are preciously invisible to the human eye, sluice to the most powerful microscopes. because of this factor he veritable ways of grimeing the microbes with dishonors so he could see them, calculate the microbe’s rate of reproduction and their lifespan. His discovery of the identification of diametric bacterium and the different disease it caused was a huge breakthrough in checkup history and the arrest of the turnment of diseases, as his work proved that what really caused diseases was. This is a significance to medicine as he discovered 21 different germs causing diseases. in 1882 he discovered a germ that causes tuberculosis, 1883 a germ that caused cholera and these were one of the tip 3 deadliest diseases. this breakthrough paved way for other scientists to take up the contend and conduct inquiry leading to new discoveries as such. Koch’s assistant Emil Behring genuine the first anti toxin which could facilitate to deflower the poison spread from bacteria in the blood stream. This was used for the successful discussion of Diphtheria in 1891 one of the top deadliest diseases. This led to a German Jewish scientist and physician Paul Ehrlich who worked on Koch’s bacteriology research lab to take on a research during the 1890s on how certain dyes could stain certain bacteria and maybe find certain chemicals that can kill them. by 1914 his team had discovered several types of ‘magic bullets’, these different compounds would have a special(prenominal) attraction to special disease-causing microbe in the body and this would hit a specific germ (that has become visible because of a specific dye) and non damage an ything else in the enduring’s body. the magic bullets dye discovered were Methylene blue (for malaria), Trypan red (for sleeping sickness) and Salvarsan (for pox).\r\nThis was a huge medical breakthrough because this will allow other scientists to developed specific do drugss to mastermind specific germs, attacking the cause of the disease preferably than treating the symptoms. this is a significant discovery because it shows us an understanding on how bacteria behaves and how to treat a disease by localise and kill. this gave a broad idea of treating medicine because not only they can target and kill syphilis, malaria but they can do this for other diseases. As a result, in 1928 a bacteriologist Alexander Fleming while alter his cluttered lab noticed that a culture of Staphylococus aureas had become contaminated with lick in his Petri dish. This spurt was called Penicillium Notatum. The function was in a shape of a ring, and the area around it seemed to be vacate o f the bacteria staphylococcus. Fleming concluded that the bacteria on the plate around the ring had been killed pip by some substances that had come from chuck. He continued to experiment with the mould and raise out (in controlled experiments) that the mould killed harmful bacteria and appears to be non-toxic to humans or animals . This was a huge scientific breakthrough because the mould is nontoxic and can kill all kinds of bacteria; if it was stranded into a drug it can be used to treat patients. Unfortunately Fleming could not isolate the mould and could not make a usefule drug to treat humans. although he wrote his discovery in 1929 the science department remained uninterested. Not Until 12 years later a braces of young scientists Howard Florey and Ernst Chain, revisited and continued Fleming’s work as a way to help military effort in solid ground warfare 2, since a lot sol croakrs die in infections than gun wounds, something needful to be done. So in Oxford Unive rsity they finally isolated the bacteria-killing substance from mould. this creation has a huge significance in medical intercession because they have created the once known ‘ call into question drug’ that could kill harmful pathogens as such, that can possibly bring round syphilis gangrene pneumonia and tuberculosis.\r\nTo prove its potential it needed to be trialed on a human. In 1941 a doctor Charles Fletcher heard of their work. he had a patient who was near ending from an bacterial infection on wound. Fletcher used some of chain’s and Florey’s penicillin on the patient and the wound made a spectacular recovery. however the patient died a few weeks later because Fletcher did not put enough penicillin to eliminate tout ensemble the bacteria in the patient’s body. Despite this case, this had proven that penicillin could do what it’s made to do. the patient only died because he did not have enough penicillin, not that it did not work. Si nce a lot of people died in infections than gunshots in World War 2, they needed a drug that can effectively heal America’s soldiers. Florey then got the American drugs Company to set produced Penicillin before D-Day, so American soldiers on the front have enough penicillin to treat all infections that will be inflicted among the troops. This is a huge significance to medical treatment because not only they created a non toxic, bacteria killing drug, the drug can cure all bacterial based diseases such a syphilis , pneumonia and tuberculosis, since they can mass produce it the drug is therefore showy and can treat almost everyone. overall the understanding od disease and treatment developed greatly in the years treatment of disease change developed greatly in the years 1860-1945 as man were able to understand…\r\n'